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N8141 Sigma-Aldrich

4-Nitroquinoline N-oxide

≥98%

Synonym: 4-NQO, 4-Nitroquinoline 1-oxide

  • CAS Number 56-57-5

  • Empirical Formula (Hill Notation) C9H6N2O3

  • Molecular Weight 190.16

  •  Beilstein Registry Number 165756

  •  EC Number 200-281-1

  •  MDL number MFCD00006738

  •  PubChem Substance ID 57654464

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Properties

Related Categories Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines More...
InChI Key   YHQDZJICGQWFHK-UHFFFAOYSA-N
assay   ≥98%
color   yellow to brown
mp   154-156 °C (lit.)
solubility   acetone: soluble, clear to hazy
storage temp.   −20°C

Description

Biochem/physiol Actions

Skin and lung tumor initiator under experimental conditions.

Packaging

1, 5 g in poly bottle

250 mg in poly bottle

Application

4-Nitroquinoline N-oxide has been used as a model compound to study its carcinogenic effects.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
VC2100000

Documents

Certificate of Analysis

Certificate of Origin


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Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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