EMAIL THIS PAGE TO A FRIEND
W6578 Sigma-Aldrich

Pyruvic-1-13C acid

(for Clinical Studies), ≥99 atom % 13C

Synonym: α-Ketopropionic acid-1-13C, 2-Oxopropionic acid-1-13C, 13C Labeled pyruvic acid, Pyruvic acid-1-13C

Purchase

Properties

Related Categories Alphabetical Listings, MRI / MRS / Hyperpolarization, P, Stable Isotopes, cGMP Products More...
Quality Level   400
isotopic purity   ≥99 atom % 13C
assay   ≥95% (CP)
bp   165 °C
mp   11-12 °C
mass shift   M+1
shipped in   dry ice
storage temp.   −20°C
SMILES string   CC(=O)[13C](O)=O
InChI   1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/i3+1
InChI key   LCTONWCANYUPML-LBPDFUHNSA-N

Description

General description

Pyruvic-1-13C is isotopic labeled precursor of pyruvic acid.

Application

Hyperpolarized 13C-labeled pyruvate and its metabolite lactate has been used to image the real time metabolic flux in solid tumors and assess tumor response to chemotherapy, radiation, and agents targeting mTOR.

Packaging

4, 5, 6 g in glass bottle

Typically, this product is available to ship immediately from stock. Contact Stable Isotopes Customer Service to discuss quantity and packaging needs.

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3265 8 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
179.6 °F - closed cup
Flash Point(C) 
82 °C - closed cup

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Articles

Dynamic Nuclear Polarization

Dynamic Nuclear Polarization (DNP) is a phenomenon by which high spin polarization, typically derived from a bath of free radical electrons, is transferred to a nuclear spin bath, enhancing the diffe...
Dr. Matthew E. Merritt
Keywords: Cancer, Catalysis, Magnetic resonance imaging, Magnetic resonance spectroscopy, Melting, Metabolism, Metabolites, Nuclear magnetic resonance spectroscopy, Positron Emission Tomography, Spectroscopy, pH measurement

MRI/MRS: Use of Isotopes in Hyperpolarization

The single greatest impediment to the use of nuclear magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) in vivo is its limited sensitivity1. Hyperpolarization promises enhance...
Pratip Bhattacharya, Ph.D.
ISOTEC® Stable Isotopes 2008 - 2010 Catalog
Keywords: Amplification, Chemical reactions, Citric Acid Cycle, Diagnostic Imaging, Magnetic resonance imaging, Magnetic resonance spectroscopy, Metabolites, Nuclear magnetic resonance spectroscopy, Spectroscopy

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?