330021S Avanti

WR304 mAb

WR304 Mouse Monoclonal Antibody (IgM), Anti-(PIP/PIP2), 1X TBS (Tris Buffered Saline) with 1mM Na2 EDTA



Related Categories Avanti Lipidomics Products, Avanti Lipidomics Toolbox, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
antibody product type   primary antibodies
assay   >95%
packaging   pkg of 1 × 0.1 mL (polypropylene tube with screw cap (330021S-100ug))
mfr. no.   Avanti Polar Lipids, 330021S
concentration   1 mg/mL (330021S-100ug)
shipped in   dry ice
storage temp.   −70°C


General description

WR304 is an antibody that binds specifically to the lipids PIP and PIP2. WR304 also neutralizes infectious HIV-1 virus and can be used to probe the presence of PIP and PIP2 in membranes in a variety of applications including inositol phosphate-dependent cell signaling pathways. This antibody was developed by the Walter Reed Army Institute of Research (WRAIR) using a targeted adjuvant protocol with liposomes containing Avanti’s Lipid A.
Formulation: WR304 is provided as a 0.2μm sterile-filtered solution in Tris buffered saline (TBS). WR304 binding to porcine brain PI(4)P is inhibited by high concentration of Ca2+ (10 mM)iv and addition of 1 mM EDTA stimulates this binding activity. PBS and other phosphate-containing buffers should not be used as they inhibit binding to the phospholipid head groupiii.


WR304 recognizes PIP and PIP2, and neutralizes HIV-1 virus.


Antigens: Brain PI(4)P


ELISA, IHC, Dot Blot, Flow cytometry and HIV-1 infectivity.

The WR304 antibody has been used for the quantitation of PIP/PIP2 in direct ELISA and Dot Blot analysis. The WR304 antibody specifically binds to PIP/PIP2 and inhibits the infectivity of HIV-1 to peripheral blood mononuclear cells (PBMC).


0.5 mL Polypropylene Tube with Screw Cap (330021S-100ug)

Storage and Stability

Store undiluted at either -20°C or -80°C.

Other Notes

Hazardous/Non-hazardous Components: This product contains no substances that, at their given concentration, are known to be hazardous to health. Therefore, there is no MSDS for this product.

Ig Class: Mouse IgM (kappa).
Antibody Source: Monoclonal antibody from BALB/c-derived hybridoma WR304.
Production: In vitro cell culture. Purification: Ultra filtration through 100 KDa cut-off filters.
Purification: Ultra filtration through 100 KDa cut-off filters.

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis (COA)

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Protocols & Articles


Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents


General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers


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