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640004P Avanti

DMABA-d4 NHS Ester

4-(dimethylamino)-2,5-dioxo-1-pyrrolidinyl ester-benzoic-2,3,5,6-d4 acid, powder

Synonym: 4-(dimethylamino)benzoic acid N-hydroxysuccinimide ester-d4

  • CAS Number 1175002-03-5

  • Empirical Formula (Hill Notation) C13H10D4N2O4

  • Molecular Weight 266.29

  •  NACRES NA.25

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Properties

Related Categories Avanti Deuterium Labeled Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 1 mg (640004P-1mg)
mfr. no.   Avanti Polar Lipids, 640004P
shipped in   dry ice
storage temp.   −20°C
SMILES string   CN(C)C1=C([2H])C([2H])=C(C(ON(C(CC2)=O)C2=O)=O)C([2H])=C1[2H]

Description

General description

The DMABA NHS ester reagents were developed by Dr. Robert Murphy’s laboratory at the University of Colorado in order to create PE derivatives where all subclasses and potentially oxidized products could be universally detected using a common precursor ion in the positive ion mode by Mass Spectrometry.

Biochem/physiol Actions

DMABA-d4 NHS Ester is a deuterium enriched 4-(dimethylamino)benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagent. It helps in assessing distribution of phosphatidylethanolamine in RAW 264.7 cells. DMABA-d4 NHS ester is used for derivatization studies. DMABA esters enable lipid quantification and profiling during biological events.

Deuterium enriched 4-(dimethylamino) benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagents (d0, d4, d6, d10) derivatize the primary amine group of lipids, such as glycerophosphoethanolamine (PE) lipid species.

Packaging

5 mL Amber Glass Screw Cap Vial (640004P-1mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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