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699855P Sigma-Aldrich

3D-(6-acyl) PHAD®

Monophosphoryl Hexa-acyl Lipid A, 3-Deacyl (Synthetic), powder

  • CAS Number 252042-59-4

  • Empirical Formula (Hill Notation) C96H184N3O21P

  • Molecular Weight 1747.47

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Properties

Related Categories Avanti Adjuvants, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (HPLC)
form   powder
packaging   pkg of 1 × 1 mg (699855P-1mg)
  pkg of 1 × 5 mg (699855P-5mg)
mfr. no.   Avanti Polar Lipids, 699855P
shipped in   dry ice
storage temp.   −20°C

Description

Other Notes

For R&D use only. Not for drug, household, or other uses.

Packaging

2 mL Amber Glass Crimp Cap Vial (699855P-1mg)

2 mL Amber Glass Crimp Cap Vial (699855P-5mg)

General description

Vaccination is well-accepted as an effective method to prevent infections by mounting pathogen-specific immune responses prior to the infection. Usually, immunization with vaccine antigens alone is not able to induce robust or long-lasting immune responses — resulting in failure of protective immunity against infections. Thus, adjuvants are required to enhance cellular or humoral immune responses upon immunization. Because vaccine adjuvants using Lipid A have proven to be safe and effective in inducing Th-1 type immune responses to heterologous proteins in animal and human vaccines, Avanti developed Phosphorylated HexaAcyl Disaccharide (PHAD®), the first fully synthetic monophosphoryl Lipid A available for use as an adjuvant in human vaccines.

Legal Information

PHAD is a registered trademark of Avanti Polar Lipids, Inc.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


Webinar - Hydrogels
Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

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