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790590P Avanti

Bicelle Blend (DMPC:DHPC (2.8:1, mol:mol))

Bicelle Blend (DMPC:DHPC (2.8:1, mol:mol)) , powder

  •  NACRES NA.25

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Properties

Related Categories Avanti Lipidomics Products, Avanti Lipidomics Toolbox, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
form   powder
packaging   pkg of 2 × 100 mg (790590P-200MG)
mfr. no.   Avanti Polar Lipids
application(s)   thin layer chromatography (TLC): 99%
shipped in   dry ice
storage temp.   −20°C

Description

General description

Bicelle blend contains 200mg of dimyristoylphosphatidylcholine (DMPC): dihexanoylphosphatidylcholine (DHPC) Pre-Mixed Bicelle (2.8:1, mol:mol). Bicelle is a discoidal lipid aggregate. It is made up of long-chain phospholipid and a detergent. The planar bilayer is generally composed of DMPC, which may have phospholipids with identical chain lengths but differ in the head group. The detergent layer is composed of a short-chain phospholipid like DHPC.

The bicelle blend is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol: https://avantilipids.com/tech-support/liposome-preparation/bicelle-preparation/

Biochem/physiol Actions

Bicelles are used as membrane mimetics for studying membrane-associated biomolecules.

Packaging

5ML Amber Glass Screw Cap Vial (790590P-200MG)

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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