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791225P Avanti

14:0 PE-DTPA(Cu)

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (copper salt), powder

  • CAS Number 2260795-18-2

  • Empirical Formula (Hill Notation) C47H94CuN7O17P

  • Molecular Weight 1123.81

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Properties

Related Categories Avanti Headgroup Modified Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 5 mg (791225P-5mg)
mfr. no.   Avanti Polar Lipids, 791225P
shipped in   dry ice
storage temp.   −20°C

Description

General description

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid or 14:0 PE-DTPA is a synthetic phosphatidylethanolamine derivative.

Inclusion of copper (Cu2+) ions in bicelles in the form of a lipid chelate resulted in a 10-fold T1 reduction and 2.7-fold increase in S/N of spectra for static experiments. This improvement would allow 2D experiments on membrane proteins in aligned lipid bilayers that typically take 3 days to be completed in <1.5 days. The technique is particularly beneficial to the study of membrane disrupting/permeating systems (such as antimicrobial peptides, toxins, amyloid peptides, and fusion peptides) whose concentration cannot be increased, as they result in nonlamellar conditions.

Application

14:0 PE-DTPA(Cu) may be usedis suitable for use for liposome preparations and liposome labelling.

Packaging

5 mL Amber Glass Screw Cap Vial (791225P-5mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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