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810106C Avanti

NBD AA

20-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino] arachidonic acid, chloroform

  • CAS Number 2254005-15-5

  • Empirical Formula (Hill Notation) C26H34 N4O5

  • Molecular Weight 482.57

  •  NACRES NA.25

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Properties

Related Categories Avanti Fluorescent Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
packaging   pkg of 1 × 1 mL (810106C-1mg)
mfr. no.   Avanti Polar Lipids, 810106C
concentration   1 mg/mL (810106C-1mg)
shipped in   dry ice
storage temp.   −70°C

Description

General description

The endocannabinoid pathway influences behavior, lipogenesis, embryologic development, and pathophysiological effects including pain, inflammation, stress, obesity, and non-alcoholic fatty liver disease. Endogenous endocannabinoids including arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG) are derived from arachidonic acid (AA). Fluorescent NBD-AA and NBD-AEA analogues are direct probes that can be used for visualizing the uptake, intracellular trafficking, and targeting of these molecules by living cells, as well as measuring the binding of endocannabinoids to cytosolic binding proteins. Importantly, direct binding studies show the affinities of the fluorescent analogues are in the same range as the respective unlabeled ligands. Fluorescent endocannabinoid probes are useful for mapping the impact of various treatments, inhibitors, etc on endocannabinoid uptake and distribution in living cells.

Packaging

5 mL Amber Glass Screw Cap Vial/Argon/Foil Bag 810106C-1mg)

Safety & Documentation

Safety Information

RIDADR 
UN 1888 6.1 / PGIII

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

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