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840008P Avanti

Lyso PAF (from Heart PC)

1-alkyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

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Properties

Related Categories Avanti Natural Lipids & Extracts, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 5 mg (840008P-5mg)
mfr. no.   Avanti Polar Lipids, 840008P
shipped in   dry ice
storage temp.   −20°C
SMILES string   O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCC
InChI   1S/C24H52NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h24,26H,5-23H2,1-4H3/t24-/m1/s1
InChI key   VLBPIWYTPAXCFJ-XMMPIXPASA-N

Description

General description

Lyso-platelet activating factor (lyso-PAF) is the alkyl homolog of lysophosphatidylcholine.

Application

Lyso PAF (from Heart PC) (1-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) has been used to study its inhibitory actions on alkyl-PAF-induced death in Swiss albino mice. It may be used as an acyl acceptor in the determination of lysophosphatidic acid (LPA) acyltransferase (LPAAT) activity.

Biochem/physiol Actions

Lyso-platelet activating factor (lyso-PAF) can stimulate inflammation in a murine model of pleurisy. It acts as a stable metabolite and a precursor of PAF. The turnover of lyso-PAF to PAF is expected to induce continued inflammation in target organs or tissues.

Packaging

5 mL Clear Glass Sealed Ampule (840008P-5mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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