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840037P Avanti

16:0 PS

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

Synonym: 1,2-dihexadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DPPS; PS(16:0/16:0); 110668

  • CAS Number 145849-32-7

  • Empirical Formula (Hill Notation) C38H73NO10PNa

  • Molecular Weight 757.95

  •  NACRES NA.25

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Properties

Related Categories Avanti PS & LPS, Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 10 mg (840037P-10mg)
  pkg of 1 × 200 mg (840037P-200mg)
  pkg of 1 × 25 mg (840037P-25mg)
  pkg of 1 × 500 mg (840037P-500mg)
mfr. no.   Avanti Polar Lipids, 840037P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Description

General description

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.

Application

16:0 PS has been used in the assay to measure interactions between purified dynamin-related protein 1 (Drp1) and synthetic liposomes.

16:0 PS may be used in liposome flotation assay to measure its interactions between purified dynamin related protein 1 (Drp1) and as a component in the lipid mixtures to prepare lipid monolayers. It has also been used to prepare liposomes by the lipid film hydration method.

Biochem/physiol Actions

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.

Packaging

20 mL Clear Glass Screw Cap Vial (840037P-200mg)

30 mL Amber Wide Mouth Bottle with Screw Cap (840037P-500mg)

5 mL Amber Glass Screw Cap Vial (840037P-10mg)

5 mL Amber Glass Screw Cap Vial (840037P-25mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Miscibility of Phospholipid Binary Mixtures - Avanti® Polar Lipids

H = High. Mixing ideal or very nearly so; phase transitions of mixture are markedly broader than those of the pure components.
Keywords: Phase transitions

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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