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840457C Avanti

16:0-18:1 PG

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

Synonym: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); POPG; PG(16:0/18:1(9Z)); 110650

  • CAS Number 268550-95-4

  • Empirical Formula (Hill Notation) C40H76O10PNa

  • Molecular Weight 770.99

  •  NACRES NA.25

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Properties

Related Categories Avanti Lipidomics Products, Avanti MS Qualitative Standards, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
packaging   pkg of 1 × 2.5 mL (840457C-25mg)
  pkg of 2 × 20 mL (840457C-1g)
  pkg of 2 × 4 mL (840457C-200mg)
  pkg of 5 × 4 mL (840457C-500mg)
mfr. no.   Avanti Polar Lipids, 840457C
concentration   10 mg/mL (840457C-25mg)
  25 mg/mL (840457C-1g)
  25 mg/mL (840457C-200mg)
  25 mg/mL (840457C-500mg)
shipped in   dry ice
storage temp.   −20°C

Description

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 16:0-18:1 PG/1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (POPG) is an anionic lipid, which possesses one negative charge per lipid.

Application

16:0-18:1 PG has been used in liposome preparation. It is suitable for use as a component in monoolein to treat purified β2-adrenergic receptor (β2AR)-T4 lysozyme (T4L)- Gαs α5 helix (GsCT)-CC chimera protein and in lipid vesicle preparation.

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840457C-1g)

5 mL Clear Glass Sealed Ampule (840457C-200mg)

5 mL Clear Glass Sealed Ampule (840457C-25mg)

5 mL Clear Glass Sealed Ampule (840457C-500mg)

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Central nervous system
RIDADR 
UN 1888 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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840035C 18:1 PS (DOPS), 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

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