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850181P Avanti

08:0 PI

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Synonym: PI(8:0/8:0)

  • CAS Number 2260795-76-2

  • Empirical Formula (Hill Notation) C25H50NO13P

  • Molecular Weight 603.64

  •  NACRES NA.25

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Properties

Related Categories Avanti PI, PIP & LPI, Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug))
  pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))
mfr. no.   Avanti Polar Lipids, 850181P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

Description

General description

Phosphatidylinositol (PI), a glycerophospholipid has a head group which carries a cyclohexanol moiety. 08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) is a PI analog with a shorter acyl chain.

Application

08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) may be used:
• as a substrate for phosphatidyl-myo-inositol mannosyltransferase (PimA) to compare the effect of non-substrate phospholipids on the activity
• as a replacement for mycobacterial membranes in enzymatic assays to measure PimA activity
• as a phospholipid (PL) standard in the ion trap-time of flight (IT-TOF) system to study the fragmentation principles of unique PLs and also used as a nonendogenous PL standard for the quantitative analysis of PLs in nut samples

Biochem/physiol Actions

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol (PI) serves as a precursor of a phosphoinositides, a class of signaling lipids.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-500ug)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
No data available
Flash Point(C) 
No data available

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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