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850310C Avanti

DOBAQ

N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium, chloroform

  • CAS Number 1360461-69-3

  • Empirical Formula (Hill Notation) C49H83NO6

  • Molecular Weight 782.19

  •  NACRES NA.25

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Properties

Related Categories Avanti Polar Lipids Products, Avanti Transfection Reagents, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
packaging   pkg of 1 × 2.5 mL (850310C-25mg)
mfr. no.   Avanti Polar Lipids, 850310C
concentration   10 mg/mL (850310C-25mg)
shipped in   dry ice
storage temp.   −20°C

Description

General description

DOBAQ is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. It is a pH-sensitive lipid.

Biochem/physiol Actions

N-(4-carboxybenzyl)-N,N-dimethyl2,3-bis(oleoyloxy)propan-1-aminium/DOBAQ displays pH-dependent ionization.

Packaging

5 mL Clear Glass Sealed Ampule (850310C-25mg)

Safety & Documentation

Safety Information

RIDADR 
UN 1888 6.1 / PGIII

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Liposome Preparation - Avanti® Polar Lipids

Liposomes (lipid vesicles) are formed when thin lipid films or lipid cakes are hydrated and stacks of liquid crystalline bilayers become fluid and swell. The hydrated lipid sheets detach during agita...
Keywords: Centrifugation, Degradations, Evaporation, Hydration reaction, Phase transitions, Sonication

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Preparation of Cationic Liposomes & Transfection of Cells - Avanti® Polar Lipids

From our library of Protocols, Sigma-Aldrich presents Preparation of Cationic Liposomes & Transfection of Cells - Avanti® Polar Lipids
Keywords: Sterilizations, Transfection

Procedure for Preparation of Cationic Lipid/Oligomer Complex - Avanti® Polar Lipids

Normal procedure for preparation of lipid:DNA complex requires suspending the cationic lipid in aqueous buffer and sonication to form small vesicles. The cationic lipid vesicles are mixed with the aq...
Keywords: Sonication

Peer-Reviewed Papers
15

References

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