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850325P Avanti

10:0 PC

1,2-didecanoyl-sn-glycero-3-phosphocholine, powder

Synonym: 1,2-dicapryl-sn-glycero-3-phosphocholine; PC(10:0/10:0)

  • CAS Number 3436-44-0

  • Empirical Formula (Hill Notation) C28H56NO8P

  • Molecular Weight 565.72

  •  NACRES NA.25

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Properties

Related Categories Avanti PC & LPC, Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 200 mg (850325P-200mg)
  pkg of 1 × 25 mg (850325P-25mg)
mfr. no.   Avanti Polar Lipids, 850325P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O
InChI   1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3
InChI key   MLKLDGSYMHFAOC-UHFFFAOYSA-N

Description

General description

10:0 PC (DDPC/1,2-didecanoyl-sn-glycero-3-phosphocholine) is a zwitterionic and shorter-acyl chain phospholipid.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

10:0 PC (DDPC/1,2-didecanoyl-sn-glycero-3-phosphocholine) may be used:
• as an internal standard to measure lipid metabolites for metabolic profiling using hydrophilic interaction liquid chromatography (HILIC)
• to prepare lipid bilayer to reconstitute Vpu (membrane protein) and for biophysical studies
•  to prepare phospholipid membrane to study lipid-induced conformation of a 27-residue Cry4Ba-α7 peptide

Biochem/physiol Actions

High or low level of phosphatidylcholine (PC) can affect energy metabolism in several organelles.

Packaging

20 mL Clear Glass Screw Cap Vial (850325P-200mg)

5 mL Clear Glass Sealed Ampule (850325P-25mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in th...
Keywords: Biochemistry

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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