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850395C Avanti

18:3 (Cis) PC

1,2-dilinolenoyl-sn-glycero-3-phosphocholine, chloroform

  • CAS Number 2701-19-1

  • Empirical Formula (Hill Notation) C44H76NO8P

  • Molecular Weight 778.05

  •  NACRES NA.25

Purchase

Properties

Related Categories Avanti PC & LPC, Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
packaging   pkg of 1 × 2.5 mL (850395C-25mg)
  pkg of 2 × 4 mL (850395C-200mg)
mfr. no.   Avanti Polar Lipids, 850395C
concentration   10 mg/mL (850395C-25mg)
  25 mg/mL (850395C-200mg)
shipped in   dry ice
storage temp.   −20°C

Description

General description

18:3 (cis) PC or 1,2-dilinolenoyl-sn-glycero-3-phosphocholine is an unsaturated glycerophospholipid, with substitution of two chains of linolenic acid at sn-1 and sn-2 positions of the glycerol backbone, along with choline as a headgroup.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:3 (cis) PC or 1,2-dilinolenoyl-sn-glycero-3-phosphocholine:
• might be used in aqueous lipid-trehalose formulations to assess the long-term storage stability of lyophilized liposomes
• might be used in phospholipid monolayer to study the instability of unsaturated phospholipids at specified conditions
• has been used in aqueous sugar formulations or liposome formulations to characterize its degradation during lyophilization

Packaging

5 mL Clear Glass Sealed Ampule (850395C-200mg)

5 mL Clear Glass Sealed Ampule (850395C-25mg)

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Central nervous system
RIDADR 
UN 1888 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
does not flash
Flash Point(C) 
does not flash

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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