850457P Sigma-Aldrich

16:0-18:1 PC

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, powder

Synonym: 1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; POPC; PC(16:0/18:1(9Z))

  • CAS Number 26853-31-6

  • Empirical Formula (Hill Notation) C42H82NO8P

  • Molecular Weight 760.08



Related Categories Avanti PC & LPC, Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 1 g (850457P-1g)
  pkg of 2 × 100 mg (850457P-200mg)
  pkg of 5 × 100 mg (850457P-500mg)
  pkg of 1 × 25 mg (850457P-25mg)
mfr. no.   Avanti Polar Lipids, 850457P
shipped in   dry ice
storage temp.   −20°C



5 mL Clear Glass Sealed Ampule (850457P-200mg)

5 mL Clear Glass Sealed Ampule (850457P-25mg)

5 mL Clear Glass Sealed Ampule (850457P-500mg)

60 mL Amber Wide Mouth Screw Cap Glass Bottle (850457P-1g)

General description

POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.

Safety & Documentation

Safety Information

NONH for all modes of transport


Certificate of Analysis

Webinar - Hydrogels
Protocols & Articles


Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents


Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers


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