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850524P Avanti

CHEMS

cholesteryl hemisuccinate, powder

Synonym: 3β-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3β-ol 3-hemisuccinate; CHS

  • CAS Number 1510-21-0

  • Empirical Formula (Hill Notation) C31H50O4

  • Molecular Weight 486.73

  •  NACRES NA.25

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Properties

Related Categories Avanti Detergents, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
form   powder
mol wt   486.73 g/mol
packaging   pkg of 1 × 1 g (850524P-1g)
  pkg of 1 × 5 g (850524P-5g)
mfr. no.   Avanti Polar Lipids, 850524P
application(s)   cell analysis: suitable
  protein quantification: suitable
shipped in   dry ice
storage temp.   −20°C
InChI   1S/C31H50O4/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1
InChI key   WLNARFZDISHUGS-MIXBDBMTSA-N

Description

General description

Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.

Application

CHEMS is suitable:
• to prepare multifunctional envelope-type nano device (MEND) by a lipid film hydration method based on electrostatic interactions
• to as a component in bolavesicle
• to prepare liposome (LS)
• for the preparation of anionic liposomes by the lipid thin film hydration and freeze/thaw technique and to encapsulate ovalbumin (OVA) and listeriolysin O (LLO)
• to prepare liposomal membranes to study its effect on the physical–chemical properties of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) liposomes

Biochem/physiol Actions

CHEMS can help to maintain the stability of dioleoylphosphatidylethanolamine (DOPE). This amphipathic lipid is used in mixtures with dioleoylphosphatidylethanolamine (DOPE) to form ′pH sensitive′ fusogenic vesicles. It can control cell growth.

Packaging

20 mL Clear Glass Screw Cap Vial (850524P-1g)

30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850524P-5g)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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