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857131P Avanti

14:0 BMP (S,R)

bis(monomyristoylglycero)phosphate (S,R Isomer) (ammonium salt), powder

Synonym: sn-(3-tetradecanoyl-2-hydroxy)-glycerol-1-phospho-sn-3′-(1′-tetradecanoyl-2′-hydroxy)-glycerol (ammonium salt); lysobisphosphatidic acid; LBPA; 110857

  • CAS Number 325466-03-3

  • Empirical Formula (Hill Notation) C34H70NO10P

  • Molecular Weight 683.89

  •  NACRES NA.25

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Properties

Related Categories Avanti Bis(Monoacylglycero)Phosphate (BMP), Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (BMP (contains 30% positional isomers), TLC)
form   powder
packaging   pkg of 1 × 10 mg (857131P-10mg)
  pkg of 1 × 5 mg (857131P-5mg)
mfr. no.   Avanti Polar Lipids, 857131P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCCCCCCCC)=O.[NH4+]

Description

General description

Bis(monoacylglycerol)phosphate (BMP)/lysobisphosphatidic acid is a phospholipid, that has two phosphate-linked glycerol molecules. This phosphate-linked glycerol molecules are present in an unusual sn-1 glycerophospho-sn-1′ glycerol stereo conformation, and each glycerol molecule esterified with fattyacid. It is usually seen in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.

Biochem/physiol Actions

Bis(monoacylglycerol)phosphate (BMP)/lysobisphosphatidic acid actively participates in cargo sorting by inducing the degradation and sorting of lipids. It also plays a major role in polyunsaturated fatty acid (PUFA) sorting in acidic organelles.

Packaging

5 mL Amber Glass Screw Cap Vial (857131P-10mg)

5 mL Amber Glass Screw Cap Vial (857131P-5mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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