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860061C Avanti

Egg SM

Sphingomyelin (Egg, Chicken), chloroform

Synonym: 16:0 SM; Hexadecanoyl Sphingomyelin; N-hexadecanoyl-D-erythro-sphingosylphosphorylcholine; N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine

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Properties

Related Categories Avanti Natural Lipids & Extracts, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
packaging   pkg of 1 × 2.5 mL (860061C-25mg)
  pkg of 2 × 20 mL (860061C-1g)
  pkg of 2 × 4 mL (860061C-200mg)
mfr. no.   Avanti Polar Lipids, 860061C
concentration   10 mg/mL (860061C-25mg)
  25 mg/mL (860061C-1g)
  25 mg/mL (860061C-200mg)
shipped in   dry ice
storage temp.   −20°C

Description

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (860061C-1g)

5 mL Clear Glass Sealed Ampule (860061C-200mg)

5 mL Clear Glass Sealed Ampule (860061C-25mg)

General description

As a major constituent of cell membranes, sphingomyelin is found at particularly high concentrations in the membranes of nerve cells (in the myelin sheaths) and red blood cells. It was previously thought to have a purely structural role, similar to the function of phosphatidylcholine, through intermolecular interactions mediated by the 2-amide group, the 3-hydroxy group and the 4,5-trans double bond of the sphingoid base. However, it is now appreciated that sphingomyelin has a high affinity for cholesterol and that these two lipids pack tightly into liquid-ordered domains among a liquid-disordered phase to form lipid rafts. These membrane microdomains are thought to function as signaling platforms that regulate the localization and interactions of proteins. But sphingomyelin does not just influence signaling as a component of lipid rafts — it is also a precursor to ceramides and other sphingolipid metabolites that comprise the sphingomyelin cycle or sphingolipid network.
Sphingomyelin and related lipids

Safety & Documentation

Safety Information

RIDADR 
UN 1888 6.1 / PGIII

Documents

Certificate of Analysis


Webinar - Hydrogels
Protocols & Articles

Articles

Fatty Acid Distribution - Tissue Types - Avanti® Polar Lipids

Fatty acid distribution determined by GC analysis of fatty acid methyl esters and is expressed in % area under curve (AUC). Minor fluctuations in the fatty acid profile from batch-to-batch should be ...
Keywords: Gas chromatography

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

Related Products

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