860076W Avanti

C18:0 GM1-d5

C18:0 GM1 Ganglioside-d5 (synthetic, ammonium salt), methanol solution

  • CAS Number 2260669-93-8

  • Empirical Formula (Hill Notation) C73H129D5N4O31

  • Molecular Weight 1568.88



Related Categories Avanti Deuterium Labeled Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (TLC)
form   methanol solution
packaging   pkg of 1 × 1 mL (860076W-100ug)
mfr. no.   Avanti Polar Lipids, 860076W
concentration   0.1 mg/mL
shipped in   dry ice
storage temp.   −20°C


General description

Gangliosides are glycosphingolipids, contains one or more residues of sialic acid. They are grouped according to the number of their sialic acid residues: one (M), two (D), or three (T). The GM1 ganglioside denotes a glycolipid that contains a monosialylated tetraose oligosaccharide (Galβ1 & 3GalNAcβ1 & 4(NeuAcα2 & 3)Galβ1 & 4Glcβ1 & 1′Cer). C18:0 GM1 ganglioside contains stearic acid as one of the fatty acid chain. These are normal components of the plasma membranes of mammalian cells and are abundant in neuronal membranes. Structurally, they possess the oligosaccharide chain constituting the hydrophilic portion in the extracellular medium and the ceramide moiety constituting the hydrophobic portion in the lipid layer of the membrane. The length and degree of unsaturation of both alkyl chains present in the ganglioside influences membrane fluidity and permeability. The ceramide portion regulates the activity of membrane-associated proteins.

Biochem/physiol Actions

Gangliosides plays an important role in cell-cell recognition, cell adhesion, contact inhibition, and tissue differentiation. GM1 ganglioside binds the cholera toxin.


2 mL Amber Glass Sealed Ampule

Safety & Documentation

Safety Information

UN1230 - class 3 - PG 2 - Methanol, solution


Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers


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