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860398P Avanti

18:0-d35 Lyso PC

1-stearoyl-d35-sn-glycero-3-phosphocholine, powder

  • CAS Number 327178-92-7

  • Empirical Formula (Hill Notation) C26H19NO7PD35

  • Molecular Weight 558.90

  •  NACRES NA.25

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Properties

Related Categories Avanti Deuterium Labeled Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
assay   >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
form   powder
packaging   pkg of 1 × 10 mg (860398P-10mg)
mfr. no.   Avanti Polar Lipids, 860398P
shipped in   dry ice
storage temp.   −20°C
SMILES string   O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2

Description

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Lysophosphatidylcholine (Lyso PC) is a bioactive proinflammatory phospholipid and a component of oxidized low-density lipoprotein (Ox-LDL). It is produced during various pathological activities.

Biochem/physiol Actions

Lysophosphatidylcholine (Lyso PC) on acylation by yeast protein Ypr140w yields phosphatidylcholine (PC). Lyso PC alters functions in a numerous cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages, and T-cells and leads to the development of atherosclerosis and inflammatory diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860398P-10mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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