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860550P Avanti

Biotin Sphingosine

omega-biotinyl D-erythro-sphingosine, powder

  • CAS Number 752987-57-8

  • Empirical Formula (Hill Notation) C28H52N4O4S

  • Molecular Weight 540.80

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Properties

Related Categories Avanti Polar Lipids Products, Avanti Sphingolipids, Avanti Sphingolipids & Ceramides, Biochemicals and Reagents, Lipids More...
form   powder
packaging   pkg of 1 × 1 mg (860550P-1mg)
mfr. no.   Avanti Polar Lipids, 860550P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [H][C@@]1(CCCCC(NCCCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@](N)([H])CO)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O

Description

General description

Biotin Sphingosine is a derivative of sphingosine. It contains a biotin moiety linked to the ω-terminal of its fatty-acid chain.

Application

Biotin Sphingosine has been used as a substrate in sphingosine kinases (SphK) assay. It has also been used to label wt- ceramide synthase 1 (CerS1) expressed in UM-SCC-22A cells, to study the interaction between CerS1-generated C18-ceramide and light chain 3 β (LC3B).

Biochem/physiol Actions

Biotin Sphingosineplays a vital role in identifying sphingosine interaction with acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A).

Packaging

5 mL Amber Glass Screw Cap Vial (860550P-1mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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