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860679P Avanti

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))

N-nervonoyl-D-erythro-sphingosine (d7), powder

  • Empirical Formula (Hill Notation) C42H74D7NO3

  • Molecular Weight 655.14

  •  NACRES NA.25

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Properties

Related Categories Avanti Deuterium Labeled Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
form   powder
packaging   pkg of 1 × 1 mg (860679P-1mg)
mfr. no.   Avanti Polar Lipids, 860679P
shipped in   dry ice
storage temp.   −20°C
SMILES string   OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]

Description

General description

C24:1 Ceramide (d18:1/24:1) is a synthetic ceramide derived from sphingosine with nervonic acid (a monounsaturated analog of lignoceric acid (24:0)). C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) is a deuterated derivative of C24:1 Ceramide (d18:1/24:1).

Application

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24:1 ceramide in skeletal muscle. It has also been used as a standard to measure C40-C44 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery.

Biochem/physiol Actions

Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma aids the prognosis of fatal outcome of coronary artery disease. C24:1 Ceramide (d18:1/24:1) in a stable isotope form is suitable for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860679P-1mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
No data available
Flash Point(C) 
No data available

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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