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870708P Avanti

08:0 Coenzyme A

octanoyl Coenzyme A (ammonium salt), powder

  • CAS Number 799812-82-1

  • Empirical Formula (Hill Notation) C29H59N10O17P3S

  • Molecular Weight 944.82

  •  NACRES NA.25

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Properties

Related Categories Avanti Coenzyme A derivatives, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
form   powder
packaging   pkg of 1 × 5 mg (870708P-5mg)
mfr. no.   Avanti Polar Lipids, 870708P
shipped in   dry ice
storage temp.   −20°C
SMILES string   O[C@@](C(NCCC(NCCSC(CCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

Description

General description

08:0 Coenzyme A, also referred as octanoyl Coenzyme A, is a medium-chain acyl CoA. It is a coenzyme A derivative of octanoic acid.

Application

08:0 Coenzyme A has been used as a substrate in microsomal ghrelin octanoyltransferase assay.

Biochem/physiol Actions

08:0 Coenzyme A acts as an intermediate in mitochondrial fatty acid β-oxidation. It hinders the activity of citrate synthase (CS) and glutamate dehydrogenase (GDH). Higher levels of octanoyl –CoA, due to reduced β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH), is observed in patients with MCADH deficiency (MCD).

Packaging

5 mL Amber Glass Screw Cap Vial (870708P-5mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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