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878115P Avanti

C16-04:0 PC

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine, powder

  • CAS Number 85405-03-4

  • Empirical Formula (Hill Notation) C28H58NO7P

  • Molecular Weight 551.74

  •  NACRES NA.25

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Properties

Related Categories Avanti Bioactive Lipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids
form   powder
packaging   pkg of 1 × 5 mg (878115P-5mg)
mfr. no.   Avanti Polar Lipids, 878115P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COCCCCCCCCCCCCCCCC)=O

Description

General description

C16-04:0 PC, also known as 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine (butanoyl-PAF), is a platelet-activating factor (PAF) analog belonging to the class of bioactive lipids. It is produced non-enzymatically in the oxidized-low density lipoprotein (Ox-LDL) particle. Butanoyl-PAF contains ether-linked hexadecyl chain at the sn-1 position and a butyryl group at the sn-2 position. It is mostly produced in body during high oxidative stress. This lipid mediator acts as a pro-inflammatory agent.

Application

C16-04:0 PC or 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine is suitable to study its physicochemical properties and its association with peptides derived from the C-terminal domains of human apolipoprotein E.

Packaging

5 mL Clear Glass Sealed Ampule (878115P-5mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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