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LM1601 Avanti

17:1 Lyso PC

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphocholine, methanol solution

  • CAS Number 1246304-62-0

  • Empirical Formula (Hill Notation) C25H50NO7P

  • Molecular Weight 507.64

  •  NACRES NA.25

Purchase

Properties

Related Categories Avanti LIPIDMAPS Quantitative MS Standards, Avanti Lipidomics Products, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
form   methanol solution
packaging   pkg of 1 × 1 mL (LM1601-1EA)
mfr. no.   Avanti Polar Lipids, LM1601
concentration   ~10 μg/mL (Refer to C of A for lot specific concentration. )
shipped in   dry ice
storage temp.   −20°C
SMILES string   O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O

Description

General description

Lysophosphatidylcholine (LPC) is a polar lipid, localized to the cell membranes of oxidized lipoproteins.

Application

17:1 Lyso PC has been used as an LIPID MAPS internal standard for lipid extraction from serum and quantification in liquid chromatography mass-spectrometry (LC-MS) analysis.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) is a bioactive molecule involved in various biological processes such as vascular reproduction, development and myelination. It is associated to the progression of atherosclerosis, with findings of high concentration of LPC in the lesions/plaques. Higher levels of LPC are also found in oxidatively damaged low-density lipoprotein (oxLDL) indicating cardiovascular disease. LPC is known to be implicated in neuronal diseases and cancer.

Packaging

2 mL Amber Glass Sealed Ampule (LM1601-1EA)

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 2
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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