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B-054 Supelco

Buspirone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

  • CAS Number 33386-08-2

  • Empirical Formula (Hill Notation) C21H31N5O2 · HCl

  • Molecular Weight 421.96

  •  MDL number MFCD00078569

  •  PubChem Substance ID 329773117

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Antidepressants, Pharmaceuticals, Illicit Drugs & Alcohol
Quality Level   100
  300
grade   certified reference material
feature   (Snap-N-Spike®)
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol (as free base)
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   −20°C
SMILES string   O=C1CC2(CCCC2)CC(N1CCCCN(CC3)CCN3C4=NC=CC=N4)=O.Cl
InChI   1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H
InChI key   RICLFGYGYQXUFH-UHFFFAOYSA-N
Gene Information   human ... HTR1A(3350)

Description

General description

Buspirone, sold under the trade name Buspar®, is an antidepressant marketed for treatment of generalized anxiety disorder and clinical depression. Suitable uses for this Certified Spiking Solution®include as starting material for calibrators and controls in antidepressant testing methods by LC/MS or GC/MS for clinical toxicology, urine drug testing, or forensic analysis applications.

Legal Information

Buspar is a registered trademark of Bristol-Myers Squibb Co.

CERILLIANT is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 1
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antidepressants

Sigma-Aldrich's Cerilliant brand offers the widest selection of Certified Spiking Solutions® for antidepressants and their metabolites and stable-labeled internal standards including a comprehensive ...
Keywords: Anti-depressants, Ion-exchange chromatography, Metabolites

Medication Monitoring Testing

Prescription monitoring requires accurate reference standards to ensure consistent and reliable results for drug confirmation and monitoring compliance.
Keywords: Anti-depressants, Anticonvulsants, Cardiovascular, Clinical, Controlled substances, Diabetes, Forensic, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Schizophrenia

Therapeutic Drug Monitoring Standards

Therapeutic drug monitoring (TDM) measures drug concentrations in blood and other biological fluids to ensure maintenance of a drug’s therapeutic range. TDM is performed routinely to guide the dosing...
Keywords: Anti-depressants, Anticonvulsants, Antifungals, Cancer, High performance liquid chromatography, Immunoassay, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

UHPLC Analysis of Buspirone on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Buspirone on Titan™ C18
Keywords: Chromatography, Mass spectrometry, Pharmaceutical

UHPLC/MS/MS Analysis of 25 Small Molecule Pharmaceutical Compounds on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of 25 Small Molecule Pharmaceutical Compounds on Ascentis® Express RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Separation

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