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Carbamazepine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

  • CAS Number 298-46-4

  • Empirical Formula (Hill Notation) C15H12N2O

  • Molecular Weight 236.27

  •  MDL number MFCD00005073

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Anticonvulsants / Antiepileptics, Anticonvulsants/Antiepileptics,
Quality Level   100
grade   certified reference material
feature   SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   −20°C
SMILES string   O=C(N)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3
InChI   1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChI key   FFGPTBGBLSHEPO-UHFFFAOYSA-N
Gene Information   human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

General description

Carbamazepine is an anticonvulsant and mood stabilizing drug used primarily in the treatment of epilepsy and neuropathic pain. Marketed under trade names including Carbatrol®, Tegretol®, Carbamaze, and Biston, carbamazepine is also used as a second line treatment for bipolar disorder and in conjunction with antipsychotic drugs for schizophrenia. Suitable uses of this Certified Spiking Solution® include as starting material for preparation of calibrators and controls in carbamazepine testing methods by GC/MS or LC/MS for clinical toxicology, pain prescription monitoring, forensic analysis, or therapeutic drug monitoring applications.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Carbatrol is a registered trademark of Pharmavene, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Tegretol is a registered trademark of Novartis Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 1
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Anticonvulsants Antiepileptics

Sigma-Aldrich's Cerilliant brand offers certified Snap-N-Spike® solutions of second-generation and newer anticonvulsants used in the treatment of fibromyalgia, neuropathic pain, and migraines. These ...
Keywords: Anticonvulsants, Controlled substances, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites

Bioanalytical Microsampling using Biocompatible SPME and Benefits over Dried Blood Spots

There is growing interest in clinical and bioanalytical research fields toward microextraction or microsampling techniques for sample isolation, storage, and transportation. This interest comes from ...
Craig Aurand
Reporter US Volume 33.3
Keywords: Adsorption, Centrifugation, Chromatography, Clinical, Evaporation, High performance liquid chromatography, Immobilization, Liquid chromatography mass spectrometry, Mass spectrometry, Phase transitions, Precipitation, Reductions, Sample preparations, Solid phase microextractions, Solvents

HPLC Analysis of Acidic and Neutral Drug Panel on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Acidic and Neutral Drug Panel on Ascentis® Express C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Hormones, Pharmaceutical

HPLC Analysis of Carbamazepine on Ascentis® Express ES-Cyano

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Carbamazepine on Ascentis® Express ES-Cyano
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

Medication Monitoring Testing

Prescription monitoring requires accurate reference standards to ensure consistent and reliable results for drug confirmation and monitoring compliance.
Keywords: Anti-depressants, Anticonvulsants, Cardiovascular, Clinical, Controlled substances, Diabetes, Forensic, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Schizophrenia

Pharmaceutical and Drug Standards for Wastewater Testing

In 2008 an Associated Press investigation identified numerous pharmaceutical and personal care products in drinking water supplies of at least 41 million Americans. The publication of this report and...
Keywords: Anti-depressants, Environmental, Hormones, Ion-exchange chromatography, Metabolites, Pharmaceutical

Therapeutic Drug Monitoring Standards

Therapeutic drug monitoring (TDM) measures drug concentrations in blood and other biological fluids to ensure maintenance of a drug’s therapeutic range. TDM is performed routinely to guide the dosing...
Keywords: Anti-depressants, Anticonvulsants, Antifungals, Cancer, High performance liquid chromatography, Immunoassay, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

UHPLC/MS Analysis of Drugs in Whole Blood on Titan™ C18 after Biocompatible Solid Phase Microextraction (BioSPME) using SPME LC Tips with C18 °Chemistry

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Drugs in Whole Blood on Titan™ C18 after Biocompatible Solid Phase Microextraction (BioSPME) using SPME LC Tips with C18 °Chemistry
Keywords: Chromatography, Clinical, Forensic, High performance liquid chromatography, Mass spectrometry, Sample preparations, Separation, Solid phase microextractions, Solvents

UHPLC/MS Analysis of Various Drug Substances on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Various Drug Substances on Titan™ C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

USP HPLC Analysis of Carbamazepine on an Ascentis® Express ES-CN Column

From our library of Articles, Sigma-Aldrich presents USP HPLC Analysis of Carbamazepine on an Ascentis® Express ES-CN Column
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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