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D-907 Supelco

Diazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Benzodiazepines, Certified Reference Materials (CRMs),
Quality Level   100
grade   certified reference material
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
drug control   Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
concentration   1.0 mg/mL in methanol
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   2-8°C
SMILES string   CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13
InChI   1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3
InChI key   AAOVKJBEBIDNHE-UHFFFAOYSA-N
Gene Information   human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

Description

General description

Diazepam is a benzodiazepine used to treat a number of conditions from anxiety and panic attacks to insomnia. This Certified Spiking Solution® is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug testing applications. Diazepam, a benzodiazpine frequently abused recreationally, is sold under the trade name Valium®.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Valium is a registered trademark of Roche Products Inc.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 2
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Benzodiazepine Standards

Benzodiazepines are a broad class of psychoactive drugs prescribed worldwide for treating numerous conditions from anxiety, seizures, and insomnia to muscle spasms, epilepsy, and alcohol withdrawal.1...
Keywords: Clinical, Forensic, Metabolites, Pharmaceutical

Bioanalytical Microsampling using Biocompatible SPME and Benefits over Dried Blood Spots

There is growing interest in clinical and bioanalytical research fields toward microextraction or microsampling techniques for sample isolation, storage, and transportation. This interest comes from ...
Craig Aurand
Reporter US Volume 33.3
Keywords: Adsorption, Centrifugation, Chromatography, Clinical, Evaporation, High performance liquid chromatography, Immobilization, Liquid chromatography mass spectrometry, Mass spectrometry, Phase transitions, Precipitation, Reductions, Sample preparations, Solid phase microextractions, Solvents

GC Analysis of Basic Drugs on Equity®-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on Equity®-5
Keywords: Chromatography, Gas chromatography, Purification

GC Analysis of Basic Drugs on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm) after SPME using 65 μm PDMS/DVB Fiber, Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm) after SPME using 65 μm PDMS/DVB Fiber, Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification, Solid phase microextractions

GC Analysis of Basic Drugs on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

HPLC Analysis of Antianxiety Drugs on Ascentis® Express C18 vs. Standard C18, Demonstrating High Throughput on Ascentis Express

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antianxiety Drugs on Ascentis® Express C18 vs. Standard C18, Demonstrating High Throughput on Ascentis Express
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Antianxiety Drugs on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antianxiety Drugs on Ascentis® Phenyl
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Anticonvulsant Drugs on Discovery® RP-AmideC16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anticonvulsant Drugs on Discovery® RP-AmideC16
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Anticonvulsants on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anticonvulsants on Discovery® C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Anticonvulsants on Discovery® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anticonvulsants on Discovery® C8
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Anxiolytic Drugs on SUPELCOSIL™ LC-8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anxiolytic Drugs on SUPELCOSIL™ LC-8
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® C8
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® Express C18, Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® Express C18, Acetonitrile Mobile Phase
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl with Acetonitrile Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl with Acetonitrile Mobile Phase
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl, Methanol Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® Express Phenyl-Hexyl, Methanol Mobile Phase
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

LC/MS Analysis of Benzodiazepines on Ascentis® Phenyl (Analyte Mix 1)

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Benzodiazepines on Ascentis® Phenyl (Analyte Mix 1)
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips
Keywords: Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Separation, Solid phase microextractions

Medication Monitoring Testing

Prescription monitoring requires accurate reference standards to ensure consistent and reliable results for drug confirmation and monitoring compliance.
Keywords: Anti-depressants, Anticonvulsants, Cardiovascular, Clinical, Controlled substances, Diabetes, Forensic, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Schizophrenia

RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

UHPLC Analysis of Deuterated Isomers on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Deuterated Isomers on Titan™ C18
Keywords: Anticonvulsants, Chromatography

UHPLC Analysis of Diazepam and Metabolites on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Diazepam and Metabolites on Ascentis® Express C18
Keywords: Chromatography, Clinical

UHPLC Analysis of Diazepam and Metabolites on Titan™ C18, Competitive Comparison

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Diazepam and Metabolites on Titan™ C18, Competitive Comparison
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Clinical, Mass spectrometry, Metabolites, Pharmaceutical

UHPLC/MS Analysis of Diazepam and Metabolites on Titan™ C18, Comparison of Flow Rate and Column Length

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Diazepam and Metabolites on Titan™ C18, Comparison of Flow Rate and Column Length
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Solvents

UHPLC/MS Analysis of Drugs in Whole Blood on Titan™ C18 after Biocompatible Solid Phase Microextraction (BioSPME) using SPME LC Tips with C18 °Chemistry

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Drugs in Whole Blood on Titan™ C18 after Biocompatible Solid Phase Microextraction (BioSPME) using SPME LC Tips with C18 °Chemistry
Keywords: Chromatography, Clinical, Forensic, High performance liquid chromatography, Mass spectrometry, Sample preparations, Separation, Solid phase microextractions, Solvents

UHPLC/MS Analysis of Heroin and Related Compounds on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Heroin and Related Compounds on Titan™ C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

UHPLC/MS Analysis of Various Drug Substances on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Various Drug Substances on Titan™ C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Sample preparations, Solid phase extractions

Peer-Reviewed Papers
15

References

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