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(1S,2R)-(+)-Ephedrine hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Synonym: (1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride, (1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride

  • CAS Number 24221-86-1

  • Linear Formula C6H5CH[CH(NHCH3)CH3]OH · HCl

  • Molecular Weight 201.69

  •  Beilstein/REAXYS Number 6118541

  •  EC Number 200-659-6

  •  MDL number MFCD00064551

  •  PubChem Substance ID 329798943

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Certified Reference Materials (CRMs), Certified Reference Materials from Cerilliant,
Quality Level   100
  300
grade   certified reference material
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol (as free base)
mp   218-220 °C (lit.)
Featured Industry   Forensics and Toxicology
Pharmaceutical (small molecule)
format   single component solution
storage temp.   −20°C
SMILES string   Cl[H].CN[C@H](C)[C@@H](O)c1ccccc1
InChI   1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10-;/m1./s1
InChI key   BALXUFOVQVENIU-GHXDPTCOSA-N

Description

General description

Ephedrine is a methamphetamine analog commonly used as a stimulant and appetite suppressant. It is also found as an active constituent in herbs used for traditional Chinese medicine, such as má huáng. This certified reference standard can be used Snap-N-Spike® as a starting material in the preparation of calibrators or controls for clinical or forensic applications or Snap-N-Shoot® in quality control testing of dietary supplements containing ephedrine.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 1
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Amphetamines-weight loss drugs

Sigma-Aldrich's Cerilliant brand provides the widest selection of Certified Spiking Solutions® for amphetamines and weight loss drugs including native and stable-labeled analogs of amphetamine, metha...
Keywords: Ion-exchange chromatography

Medication Monitoring Testing

Prescription monitoring requires accurate reference standards to ensure consistent and reliable results for drug confirmation and monitoring compliance.
Keywords: Anti-depressants, Anticonvulsants, Cardiovascular, Clinical, Controlled substances, Diabetes, Forensic, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Schizophrenia

Phytochemical Snap-N-Shoot® Reference Solutions

Sigma-Aldrich's Cerilliant brand offers Snap-N-Shoot® reference solutions and mixes for several botanicals including Turmeric, Ephedra, Ginkgo biloba, Ginseng, and Green tea. Several of these referen...
Keywords: Ion-exchange chromatography

Peer-Reviewed Papers
15

References

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D-122 Diethylpropion-D10 hydrochloride solution, 100 μg/mL in methanol (with 1% 1 M HCl, (as free base)), certified reference material, ampule of 1 mL, Cerilliant®
E-023 (1R,2S)-(−)-Ephedrine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
E-025 (1S,2R)-(+)-Ephedrine-d3 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
E-026 (1S,2R)-(+)-Ephedrine-d3 hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
M-129 (1R,2S)-(-)-N--Methylephedrine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
N-043 (±)-Norephedrine-d3 hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
N-046 (+)-Norpseudoephedrine hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-035 (S,S)-(+)-Pseudoephedrine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
P-036 (R,R)-(-)-Pseudoephedrine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
P-038 (±)-Phenylpropanolamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-056 (1S,2S)-(+)-Pseudoephedrine-d3 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-078 R-(-)-Phenylephrine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
P-079 (±)-Phenylephrine-d3 hydrochloride solution, 100 μg/mL in methanol with 5% 1 M HCl (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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