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E-060 Supelco

17β-Estradiol solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

  • CAS Number 50-28-2

  • Empirical Formula (Hill Notation) C18H24O2

  • Molecular Weight 272.38

  •  MDL number MFCD00003693

  •  PubChem Substance ID 329798978

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Biomarkers and Metabolomics Standards, Certified Reference Materials (CRMs),
grade   certified reference material
InChI Key   VOXZDWNPVJITMN-ZBRFXRBCSA-N
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in acetonitrile
format   single component solution
storage temp.   2-8°C

Description

General description

A Certified Spiking Solution® suitable for use as starting material in calibrators, controls, or linearity standards for a variety of LC/MS or GC/MS applications from endocrinology to clinical and diagnostic testing. Estradiol is a sex hormone prescribed under the trade names Vagifem®, Estring®, Evamist, Elestrin®, Estrace®, and Estrogel® as a treatment for hypoestrogenism.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Elestrin is a registered trademark of Azur Pharma

Estrace is a registered trademark of Warner Chilcott Company, LLC

Estring is a registered trademark of Pfizer Health AB

Estrogel is a registered trademark of Ascend Therapeutics, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Vagifem is a registered trademark of Novo Nordisk A/S Corp.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1648 3 / PGII
WGK Germany 
2
Flash Point(F) 
35.6 °F
Flash Point(C) 
2 °C

Documents

Certificate of Analysis

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Protocols & Articles

Articles

HPLC Analysis of Conjugated Estrogens on Discovery® HS C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Conjugated Estrogens on Discovery® HS C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Hormones

HPLC Analysis of Estrogens on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Estrogens on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Steroids on Ascentis® C18 (Mobile phase: 55:45)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Steroids on Ascentis® C18 (Mobile phase: 55:45)
Keywords: Chromatography, Clinical, High performance liquid chromatography

HPLC Analysis of Steroids on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Steroids on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Steroids on Ascentis® RP-Amide (Mobile phase: 55:45)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Steroids on Ascentis® RP-Amide (Mobile phase: 55:45)
Keywords: Chromatography, Clinical, High performance liquid chromatography

Hormone Standards

Over the past 17 years, hormone testing has increased significantly in the clinical laboratory setting as advances in the specificity and selectivity of LC-MS/MS technology have enabled hormones to s...
Keywords: Clinical, Clinical Chemistry, Diagnostic, Diseases, Endocrinology, High performance liquid chromatography, Hormones, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites

Hyper-Fast Separations on Ascentis® Express 2.7 μm at Half the Pressures of sub-2 μm Columns

From our library of Articles, Sigma-Aldrich presents Hyper-Fast Separations on Ascentis® Express 2.7 μm at Half the Pressures of sub-2 μm Columns
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

LC/MS/MS Analysis of Estradiol (Underivatized) from Patient Serum on Titan™ C18, 10 cm Column

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Estradiol (Underivatized) from Patient Serum on Titan™ C18, 10 cm Column
Keywords: Chromatography, Clinical, High performance liquid chromatography, Hormones, Liquid chromatography mass spectrometry, Mass spectrometry, Solvents

LC/MS/MS Analysis of Estradiol (Underivatized) from Patient Serum on Titan™ C18, 5 cm Column

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Estradiol (Underivatized) from Patient Serum on Titan™ C18, 5 cm Column
Keywords: Chromatography, Clinical, High performance liquid chromatography, Hormones, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Solid phase extractions, Solvents

Mitigation of Deuterium Scrambling in Stable-Labeled Internal Standards during LC-MS MS Analysis

Improvements in LC-MS/MS sensitivity and multiple reaction monitoring (MRM) capabilities are resulting in further adoption of LC-MS/MS technology in clinical settings. One specific clinical challenge...
Authors: Joshua Cooper1, Billy Molloy2, Huahua Jian1, Lisa Calton2, Derrell Johnson1, Isil Dilek1, Uma Sreenivasan1, Don Cooper2
1Cerilliant Corporation, 811 Paloma Drive, Suite A, Round Rock, TX 78665 2 Waters Corporation, Atlas Park, Simonsway, Manchester, M22 5 PP UKCONCLUSIONS
Keywords: Clinical, High performance liquid chromatography, Hormones, Liquid chromatography mass spectrometry, Mass spectrometry, Nuclear magnetic resonance spectroscopy, Phase transitions

Steroid Standards

Over the past 20 years the prevalence rate of illicit anabolic steroid use among US high school students has ranged from 2.2-6.1%.1 Anabolic steroids such as androstene, androsterone, boldenone and b...
Keywords: Cancer, Clinical, Clinical Chemistry, Diagnostic, Diseases, Endocrinology, High performance liquid chromatography, Hormones, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites

UHPLC Analysis of Conjugated Estrogens on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Conjugated Estrogens on Ascentis® Express C18
Keywords: Chromatography, Clinical, Solvents

UHPLC Analysis of Conjugated Estrogens on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Conjugated Estrogens on Titan™ C18
Keywords: Chromatography, Clinical, Solvents

UHPLC/MS Analysis of Estradiols using Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Estradiols using Ascentis® Express C18
Keywords: Mass spectrometry

Peer-Reviewed Papers
15

References

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