• USA Home
  • F-017 - (±)-Flecainide solution

EMAIL THIS PAGE TO A FRIEND
F-017 Supelco

(±)-Flecainide solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Purchase

Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Cardiac Drug Standards, Cardiac Drugs,
grade   certified reference material
InChI Key   DJBNUMBKLMJRSA-UHFFFAOYSA-N
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   −20°C

Description

General description

Flecainide, marketed under trade names such as Almarytm, Apocard, Ecrinal®, and Flécaine, is a class Ic antiarrhythmic drug used to prevent and treat a variety of cardiac arrhythmias. This Certified Spiking Solution® is suitable for use as a starting material in the preparation of calibrators, controls, or linearity standards in flecainide therapeutic drug monitoring methods by LC/MS or LC that ensure patients remain within the drug’s narrow therapeutic range.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Ecrinal is a registered trademark of Laboratoires Asepta Corporation Monaco

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
Flash Point(F) 
48.2 °F
Flash Point(C) 
9 °C

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles

Articles

Cardiac Drugs

Worldwide cardiovascular disease (CVD) prevalence is increasing, with countries such as China projecting a 73% increase in their CVD rates by 20301 and England projecting a 15% increase by 2020.2 Nea...
Keywords: Anticoagulants, Antihypertensives, Cardiovascular, Chemical vapor deposition, Clinical, Diagnostic, Forensic, Ion-exchange chromatography, Metabolites

Investigating Matrix Interference in Analysis of Antiarrhythmic Cardiac Drugs in Plasma

For efficient therapeutic drug monitoring, it is important for clinicians to have access to fast and robust analytical methods for accurate assessment of drug efficacy. Industrial trends toward highl...
Keywords: Chromatography, Filtration, High performance liquid chromatography, Immunoassay, Mass spectrometry, Metabolites, Phase transitions, Precipitation, Reversed-phase chromatography, Sample preparations, Separation, Solid phase extractions, Solvents

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC after Sample Prep using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC after Sample Prep using HybridSPE®-Phospholipid
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Sample preparations, Separation, Solid phase extractions, Solvents

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC: Improvement in Analyte Response after Solid Phase Extraction (SPE) using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC: Improvement in Analyte Response after Solid Phase Extraction (SPE) using HybridSPE®-Phospholipid
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Precipitation, Sample preparations, Separation, Solid phase extractions, Solvents

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Separation, Solvents

LC/MS Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC following Sample Prep using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC following Sample Prep using HybridSPE®-Phospholipid
Keywords: Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Solid phase extractions, Solvents

LC/MS Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Reversed-phase chromatography, Separation, Solid phase extractions

Matrix Inferference in Analysis of Cardiac Drugs in Plasma

For efficient therapeutic drug monitoring, it is important for clinicians to have access to fast and robust analytical methods to ensure accurate assessment of drug efficacy. Industrial trends toward...
Craig Aurand
Reporter US Volume 31.1
Keywords: Chromatography, Filtration, High performance liquid chromatography, Immunoassay, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites, Phase transitions, Precipitation, Reversed-phase chromatography, Sample preparations, Separation, Solid phase extractions, Solvents

Therapeutic Drug Monitoring Standards

Therapeutic drug monitoring (TDM) measures drug concentrations in blood and other biological fluids to ensure maintenance of a drug’s therapeutic range. TDM is performed routinely to guide the dosing...
Keywords: Anti-depressants, Anticonvulsants, Antifungals, Cancer, High performance liquid chromatography, Immunoassay, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?