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L-019 Supelco

Lamotrigine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

  • CAS Number 84057-84-1

  • Empirical Formula (Hill Notation) C9H7Cl2N5

  • Molecular Weight 256.09

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Anticonvulsants / Antiepileptics, Anticonvulsants/Antiepileptics,
Quality Level   100
grade   certified reference material
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   −20°C
SMILES string   Nc1nnc(c(N)n1)-c2cccc(Cl)c2Cl
InChI   1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
InChI key   PYZRQGJRPPTADH-UHFFFAOYSA-N
Gene Information   human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

General description

Lamotrigine is an anticonvulsant approved for treatment of epilepsy and bipolar disorder. Sold under the trade name Lamictal®, this phenyltriazine analog also is used off-label for treatment of clinical depression. This Snap-N-Spike® Reference Solution is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as forensic analysis and clinical toxicology.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

Lamictal is a registered trademark of GlaxoSmithKline LLC

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 1
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Anticonvulsants Antiepileptics

Sigma-Aldrich's Cerilliant brand offers certified Snap-N-Spike® solutions of second-generation and newer anticonvulsants used in the treatment of fibromyalgia, neuropathic pain, and migraines. These ...
Keywords: Anticonvulsants, Controlled substances, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites

Medication Monitoring Testing

Prescription monitoring requires accurate reference standards to ensure consistent and reliable results for drug confirmation and monitoring compliance.
Keywords: Anti-depressants, Anticonvulsants, Cardiovascular, Clinical, Controlled substances, Diabetes, Forensic, Gas chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Schizophrenia

Therapeutic Drug Monitoring Standards

Therapeutic drug monitoring (TDM) measures drug concentrations in blood and other biological fluids to ensure maintenance of a drug’s therapeutic range. TDM is performed routinely to guide the dosing...
Keywords: Anti-depressants, Anticonvulsants, Antifungals, Cancer, High performance liquid chromatography, Immunoassay, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

Peer-Reviewed Papers
15

References

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L-022 Lamotrigine-13C, 15N4 solution, 500 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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