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P-055 Supelco

Propranolol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

  • CAS Number 318-98-9

  • Empirical Formula (Hill Notation) C16H21NO2·HCl

  • Molecular Weight 295.80

  •  EC Number 200-659-6

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Cardiac Drugs, Certified Reference Materials (CRMs),
grade   certified reference material
InChI Key   ZMRUPTIKESYGQW-UHFFFAOYSA-N
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol (as free base)
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   −20°C

Description

General description

A certified reference solution suitable for use as starting material in calibrators and controls for LC/MS or GC/MS testing methods in clinical and diagnostic testing, urine drug testing, forensic analysis, or clinical toxicology. Propranolol is a sympatholytic non-selective beta blocker used to treat a variety of medical conditions including hypertension, anxiety and panic. The drug is sold under numerous brand names such as Inderal®, Avlocardyl, Deralin, and Dociton.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

Inderal is a registered trademark of Cranford Pharmaceuticals, LLC

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
Flash Point(F) 
48.2 °F
Flash Point(C) 
9 °C

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Bioanalytical Microsampling using Biocompatible SPME and Benefits over Dried Blood Spots

There is growing interest in clinical and bioanalytical research fields toward microextraction or microsampling techniques for sample isolation, storage, and transportation. This interest comes from ...
Craig Aurand
Reporter US Volume 33.3
Keywords: Adsorption, Centrifugation, Chromatography, Clinical, Evaporation, High performance liquid chromatography, Immobilization, Liquid chromatography mass spectrometry, Mass spectrometry, Phase transitions, Precipitation, Reductions, Sample preparations, Solid phase microextractions, Solvents

Cardiac Drugs

Worldwide cardiovascular disease (CVD) prevalence is increasing, with countries such as China projecting a 73% increase in their CVD rates by 20301 and England projecting a 15% increase by 2020.2 Nea...
Keywords: Anticoagulants, Antihypertensives, Cardiovascular, Chemical vapor deposition, Clinical, Diagnostic, Forensic, Ion-exchange chromatography, Metabolites

HPLC Analysis of Propranolol Enantiomers on Astec® CHIROBIOTIC® T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Propranolol Enantiomers on Astec® CHIROBIOTIC® T
Keywords: Antihypertensives, Chromatography, High performance liquid chromatography, Pharmaceutical

LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Drugs in Plasma on Ascentis® Express C18 after Extraction using SPME LC Tips
Keywords: Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Separation, Solid phase microextractions

SFC Analysis of Propranolol Enantiomers on Astec® Cellulose DMP, Methanol Additive

From our library of Articles, Sigma-Aldrich presents SFC Analysis of Propranolol Enantiomers on Astec® Cellulose DMP, Methanol Additive
Keywords: Chromatography, Pharmaceutical, Supercritical fluid chromatography

Therapeutic Drug Monitoring Standards

Therapeutic drug monitoring (TDM) measures drug concentrations in blood and other biological fluids to ensure maintenance of a drug’s therapeutic range. TDM is performed routinely to guide the dosing...
Keywords: Anti-depressants, Anticonvulsants, Antifungals, Cancer, High performance liquid chromatography, Immunoassay, Ion-exchange chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

Two Distinct Sample Prep Approaches to Overcome Matrix Effect in LC/MS of Serum or Plasma Samples

This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.
Keywords: Clinical, Forensic, High performance liquid chromatography, Mass spectrometry, Phase transitions, Precipitation, Reductions, Solid phase extractions, Solid phase microextractions, Solvents

UHPLC-MS Analysis of Basic Drugs and Metabolites with Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC-MS Analysis of Basic Drugs and Metabolites with Titan™ C18
Keywords: Chromatography, Mass spectrometry, Metabolites

UHPLC/MS Analysis of Drugs in Whole Blood on Titan™ C18 after Biocompatible Solid Phase Microextraction (BioSPME) using SPME LC Tips with C18 °Chemistry

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Drugs in Whole Blood on Titan™ C18 after Biocompatible Solid Phase Microextraction (BioSPME) using SPME LC Tips with C18 °Chemistry
Keywords: Chromatography, Clinical, Forensic, High performance liquid chromatography, Mass spectrometry, Sample preparations, Separation, Solid phase microextractions, Solvents

UHPLC/MS Analysis of Various Drug Substances on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Various Drug Substances on Titan™ C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

Peer-Reviewed Papers
15

References

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Add to Cart

P-085 (±)-Propranolol-D7 (ring-D7) solution, 100 μg/mL in methanol with 5% 1 M HCl, ampule of 1 mL, certified reference material, Cerilliant®

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