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V-002 Supelco

Verapamil hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

  • CAS Number 152-11-4

  • Empirical Formula (Hill Notation) C27H38N2O4·HCl

  • Molecular Weight 491.06

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Cardiac Drugs, Certified Reference Materials (CRMs),
Quality Level   100
grade   certified reference material
feature   Snap-N-Spike®/Snap-N-Shoot®
packaging   ampule of 1 mL
mfr. no.   Cerilliant®
concentration   1.0 mg/mL in methanol (as free base)
Featured Industry   Pharmaceutical (small molecule)
format   single component solution
storage temp.   2-8°C
SMILES string   Cl.COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
InChI   1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
InChI key   DOQPXTMNIUCOSY-UHFFFAOYSA-N
Gene Information   human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

Description

General description

Verapamil, a phenylalkylamine analog, is used to treat high blood pressure and angina. This analytical reference standard is applicable for use as starting material in calibrators or controls for verapamil testing methods by LC-MS/MS or GC-MS. A calcium channel blocker, verapamil is sold under trade names Calan® and Covera-HS®.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation

Calan is a registered trademark of G.D. Searle & Co.

Covera-HS is a registered trademark of G.D. Searle, LLC

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 1
Flash Point(F) 
49.5 °F - closed cup
Flash Point(C) 
9.7 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Cardiac Drugs

Worldwide cardiovascular disease (CVD) prevalence is increasing, with countries such as China projecting a 73% increase in their CVD rates by 20301 and England projecting a 15% increase by 2020.2 Nea...
Keywords: Anticoagulants, Antihypertensives, Cardiovascular, Chemical vapor deposition, Clinical, Diagnostic, Forensic, Ion-exchange chromatography, Metabolites

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18
Keywords: Antihypertensives, Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Precipitation, Solid phase extractions

UHPLC Analysis of Verapamil and Metabolites on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Verapamil and Metabolites on Titan™ C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

Peer-Reviewed Papers
15

References

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