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01-208 Sigma-Aldrich

IGF-I, somatomedins, insulin-like growth factors

The IGF-I protein, somatomedins, insulin-like growth factors (resistant to IGFBPs) is available in a 25 µg format.

  •  eCl@ss 32160405

  •  NACRES NA.41

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Properties

biological source   human
application(s)   cell analysis: suitable (cell culture)
shipped in   dry ice
Quality Level   100
mfr. no.   Upstate®
input   sample type epithelial cells
sample type mesenchymal stem cell(s)
sample type neural stem cell(s)
NCBI accession no.   NM_000618.2
UniProt accession no.   P01343
  P05019
Gene Information   human ... IGF1(3479)

Description

General description

Product Source: Recombinant human IGF-I expressed in E. coli.

Recombinant human IGF-I (Receptor Grade) expressed in E.coli. Human insulin-like growth factor-I (IGF-I) is a single chain 70 amino acid polypeptide that shares structural homology with insulin and human IGF-II. IGF-I plays a critical role in growth, differentiation and development via autocrine, paracrine and endocrine mechanisms. It is a mitogen and also has effects on cell migration and differentiation. IGF-I is a regulator of metabolism and is also implicated in the pathophysiology of cancer, diabetes and obesity.

Physical form

Lyophilized from 0.1M acetic acid

Sterilized through a 0.2 micron membrane filter

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Quality

Routinely evaluated in in chicken embryo fibroblasts over control cultures without IGF-I

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles
Peer-Reviewed Papers
15

References

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