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06-1090 Sigma-Aldrich

Anti-Interleukin 13 (IL-13) Antibody

Synonym: interleukin 13

  •  eCl@ss 32160702

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Properties

Related Categories Antibodies, Primary Antibodies More...
gene symbol   ALRH(260328)
  IL13(3596)
format   Affinity Purified
molecular weight   ~14 kDa observed.
The predicted MW is ~16 kDa, however the cleaved mature form of IL-13 is ~13-14 kDa.
application(s)   Immunohistochemistry
  Western Blotting
clone   Polyclonal Antibody
concentration   Please refer to the Certificate of Analysis for the lot-specific concentration.
host   Rabbit
species reactivity   Chimpanzee
  Human
  Rhesus Macaque
Species Reactivity Notes   Demonstrated to react with human.
Predicted to react with rhesus monkey and chimpanzee based on 100% sequence homology.
NCBI accession no.   NP_002179
UniProt accession no.   P35225
gene symbol   BHR1
  IL-13
  P600
shipped in   1
Quality Assurance   Evaluated by Western Blot on IL-13 human recombinant protein.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected 10 µg of IL-13 human recombinant protein.

Description

Analysis Note

Control
IL-13 human recombinant protein

Application

Immunohistochemistry Analysis: A 1:200 dilution from a previous lot detected Interleukin-13 in human lung and heart tissue.
Note - Optimal Staining with Citrate pH 6.0, Epitope Retrieval Method.

General description

Interleuken-13 (IL-13) is an immunoregulatory protein produced by activated T-cell lymphocytes. The biological activities of IL-13 include the stimulation of B-cell proliferation and immunoglobulin production. Also some of its biological activity is tied to and shows significant overlap with IL-4 including; anti-inflammatory actions in monocytes, production of cytokines and inducing enzymatic acid-metabolism on bronchial epithelial cells. IL-13 is a necessary factor in allergen-induced inflammation of the airway and for the production of mucus.

Immunogen

KLH-conjugated linear peptide corresponding to the mature chain of Interleukin-13 (IL-13).

Specificity

This antibody recognizes the mature chain of Interleukin-13.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles
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