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07-590 Sigma-Aldrich

Anti-Ago 2 Antibody

Anti-Ago 2 Antibody is a Rabbit Polyclonal Antibody for detection of Ago 2 also known as argonaute 2 & has been tested in WB.

  •  eCl@ss 32160702

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Properties

Related Categories Antibodies, Primary Antibodies More...
packaging   200 µg (07-590-25UG)
  25 μg (07-590-25UG)
gene symbol   AGO2(27161)
trade name   Upstate
brand family   Upstate
format   Purified
molecular weight   100 kDa
application(s)   Western Blotting
isotype   IgG
clone   Polyclonal Antibody
concentration   Please refer to the Certificate of Analysis for the lot-specific concentration.
host   Rabbit
species reactivity   Human
NCBI accession no.   NP_036286.2
UniProt accession no.   Q9UKV8
gene symbol   Argonaute-2
  EIF2C2
  MGC3183
  PPD
  Q10
shipped in   3
Quality Assurance   Routinely evaluated by immunoblot in RIPA and cytosolic lysates from HeLa cells.

Description

Analysis Note

Control
HeLa cell lysate, HL-60 cell lysate

General description

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

Provides endonuclease activity to RNA-induced silencing complexes (RISC). Cleaves siRNA/mRNA heteroduplexes bound to RISC. Essential for embryonic development as well as RNA-mediated gene silencing (RNAi).

Immunogen

GST fusion protein corresponding to residues 7-48 of human argonaute 2 (Ago2).

Specificity

Recognizes Ago 2, also known as eukaryotic translation initiation factor 2C, 2 (EIF2C 2), MGC3183 and Q10.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Articles

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Peer-Reviewed Papers
15

References

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