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1.00002 SAFC

Tri-n-butyl phosphate

EMPROVE® EXPERT Ph Eur

Synonym: TBP, TBPA, Tributyl phosphate

  • CAS Number 126-73-8

  • Linear Formula (CH3(CH2)3O)3PO

  • Molecular Weight 266.31

  •  Beilstein/REAXYS Number 1710584

  •  MDL number MFCD00009436

  •  EC Index Number 204-800-2

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Properties

Agency/Method   Ph. Eur.
Quality Level   500
vapor density   9.2 (vs air)
vapor pressure   27 mmHg ( 178 °C)
  7.3 mmHg ( 150 °C)
product line   EMPROVE® Expert
autoignition temp.   770 °F
potency   1550 mg/kg LD50, oral (Rat)
  >3100 mg/kg LD50, skin (Rabbit)
refractive index   n20/D 1.424 (lit.)
bp   180-183 °C/22 mmHg (lit.)
mp   −79 °C (lit.)
transition temp   flash point 146 °C
solubility   6 g/L
density   0.979 g/mL at 25 °C (lit.)
SMILES string   CCCCOP(=O)(OCCCC)OCCCC
InChI   1S/C12H27O4P/c1-4-7-10-14-17(13,15-11-8-5-2)16-12-9-6-3/h4-12H2,1-3H3
InChI key   STCOOQWBFONSKY-UHFFFAOYSA-N
storage conditions   Store at +15°C to +25°C.

Description

Application

The specification of the product is part of the Emprove® Material Qualification Dossier and can be found under "General Properties".

Analysis Note

Evaporation Number: <0.001

Purity (GC): ≥ 99 %
Identity (IR-spectrum): passes test
Appearance: passes test
Acidity: passes test
Chloride (Cl): ≤ 200 ppm
Heavy metals (as Pb): ≤ 20 ppm
Density (d 25/25): 0.966 - 0.986
Refractive index (n 25/D): 1.4205 - 1.4225
n-Butyl alcohol (GC): ≤ 1000 ppm
Other residual solvents (ICH Q3C): excluded by manufacturing process
Related substances (Highest single impurity): ≤ 0.1 %
Related substances (Sum of all impurities): ≤ 0.3 %
Water (according to Karl Fischer): ≤ 0.1 %
Total aerobic microbial count (TAMC): ≤ 1000 CFU/ml
Total combined yeasts/moulds count (TYMC): ≤ 100 CFU/ml
Bacterial endotoxins: ≤ 10 I.U./ml
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).

Corresponds to Ph Eur

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

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