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1.00864 SAFC

Ethyl acetate

EMPROVE® ESSENTIAL Ph Eur,BP,NF

Synonym: EtOAc, Ethyl ethanoate, Acetic ester, Ethyl ester

  • CAS Number 141-78-6

  • Linear Formula CH3COOC2H5

  • Molecular Weight 88.11

  •  Beilstein/REAXYS Number 506104

  •  MDL number MFCD00009171

  •  EC Index Number 205-500-4

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Properties

Agency/Method   BP
  NF
  Ph. Eur.
Quality Level   500
vapor density   3 (20 °C, vs air)
vapor pressure   73 mmHg ( 20 °C)
product line   Emprove® Essential
assay   98.0-102.0% (GC)
form   liquid
autoignition temp.   801 °F
potency   5620 mg/kg LD50, oral (Rat)
  >18000 mg/kg LD50, skin (Rabbit)
expl. lim.   2.2-11.5 %, 38 °F
refractive index   n20/D 1.3720 (lit.)
bp   76.5-77.5 °C (lit.)
mp   −84 °C (lit.)
transition temp   flash point -4 °C
solubility   85.3 g/L
density   0.902 g/mL at 25 °C (lit.)
SMILES string   CCOC(C)=O
InChI   1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
InChI key   XEKOWRVHYACXOJ-UHFFFAOYSA-N
storage conditions   Store at +15°C to +25°C.

Description

Application

The specification of the product is part of the Emprove® Material Qualification Dossier and can be found under "General Properties".

Analysis Note

Assay (GC): 98.0 - 102.0%
Identity (IR): conforms
Appearance of solution: conforms
Acidity (Ph Eur, BP): conforms
Acidity (NF): conforms
Density (d 20 °C/20 °C): 0.898 - 0.902
Density (d 25 °C/25 °C): 0.894 - 0.898
Refractive index (n 20/D): 1.370 - 1.373
Acetaldehyde (GC): ≤ 0.1%
Ethyl isobutyl ether (GC): ≤ 0.1%
Methyl compounds (GC): ≤ 0.1%
Other impurities (GC): ≤ 0.3%
Related substances (GC): ≤ 0.2%
Residual solvents class 3 (ICH Q3C): <0.5
Readily carbonizable substances: conforms
Evaporation residue: ≤ 0.0030%
Water: ≤ 0.10%
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Conforms to Ph Eur, BP, NF.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

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