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1.01040 Supelco

2-Propanol

gradient grade for liquid chromatography LiChrosolv®

Synonym: sec-Propyl alcohol, IPA, Isopropanol, Isopropyl alcohol

  • CAS Number 67-63-0

  • Linear Formula (CH3)2CHOH

  • Molecular Weight 60.10

  •  Beilstein/REAXYS Number 635639

  •  MDL number MFCD00011674

  •  EC Index Number 200-661-7

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Properties

Quality Level   100
vapor density   2.1 (vs air)
vapor pressure   33 mmHg ( 20 °C)
  43 hPa ( 20 °C)
  44 mmHg ( 25 °C)
assay   ≥99.9% (GC)
form   liquid
autoignition temp.   750 °F
potency   5045 mg/kg LD50, oral (Rat)
  12800 mg/kg LD50, skin (Rabbit)
expl. lim.   2.0-12.7 %, 93 °C
application(s)   LC/MS: suitable
refractive index   n20/D 1.377 (lit.)
pH   7 (20 °C)
bp   82 °C (lit.)
mp   −89.5 °C (lit.)
transition temp   flash point 12 °C
density   0.785 g/mL at 25 °C (lit.)
SMILES string   CC(C)O
InChI   1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
InChI key   KFZMGEQAYNKOFK-UHFFFAOYSA-N
storage conditions   Store at +5°C to +30°C.

Description

General description

With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.05 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Gradient grade (at 235 nm): ≤ 1.0 mAU
Gradient grade (at 254 nm): ≤ 1.0 mAU
Transmission (Checking after purging with N₂ (at 220 nm)): ≥ 80 %
Transmission (Checking after purging with N₂ (at 230 nm)): ≥ 90 %
Transmission (Checking after purging with N₂ (from 250 nm)): ≥ 99 %
  Filtered by 0.2 µm filter

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Protocols & Articles

Articles

Detection and Determination of Caffeine, Taurine and Arginine in Shampoos by HPTLC

During the last few years a new trend in hair care products (shampoos) has become apparent. The cleaning ability of the product is no longer the primary focus as the cosmetic industry has started to ...
Keywords: Adsorption, Chromatography, Cosmetics, Derivatizations, Mass spectrometry, Nuclear magnetic resonance spectroscopy, Separation, Thin layer chromatography

Determination of Caffeine in Energy Drinks with HPTLC-MS

An energy drink is a beverage that contains stimulants such as caffeine and taurine in additions to sugar, water, dyes and aromatics. Caffeine belongs to the alkaloid family, and it is a stimulator o...
Keywords: Addition reactions, Central Nervous System, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Separation, Thin layer chromatography

Determination of Quinine in Tonic Water and Caffeine in Coffee and Cola drinks using TLC-MS

High Performance Thin Layer Chromatography coupled with Mass spectrometry (HPTLC–MS) is an analytical technique that requires low-level of sample preparation. Here it is illustrated with the determin...
Keywords: Chromatography, Gene expression, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Separation, Thin layer chromatography

Determination of UV filter in sun cream using TLC-MS

The analytical verification of cosmetic products can be a challenging task. Formulations like creams, balms or lotions are complex matrices with respect to chromatography, so low-level sample prepara...
Keywords: Chromatography, Filtration, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, PAGE, Sample preparations, Separation, Thin layer chromatography

Proper mobile phase preparation to minimize contaminants

Mobile phase components (water, solvents and buffers) are not only used for making mobile phase but also for preparation of samples, standards and blanks as well as rinsing of bottles and vials and h...
Keywords: Buffers, Chromatography, Evaporation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Molecular biology, Precipitation, Purification, Reductions, Separation, Solvents, Titrations

Sample prep-free determination of Arginine and Taurine in shampoo by using TLC-MS

The application of modern thin-layer chromatography (TLC) offers a lot of advantages especially in the field of cosmetics. The ingredients can usually be separated directly from complex matrices and ...
Keywords: Chromatography, Cosmetics, Filtration, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, PAGE, Phase transitions, Sample preparations, Thin layer chromatography

Sample prep-free determination of Caffeine in shampoo by using TLC-MS

The analysis of shampoo for caffeine determination is an excellent application to demonstrate the easy handling and good performance of TLC-MS (thin layer chromatography – mass spectrometry) using th...
Keywords: Chromatography, Filtration, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, PAGE, Sample preparations, Separation, Thin layer chromatography

Solvents for Liquid Chromatography LiChrosolv®

For perfect high-performance liquid chromatography (HPLC) results, high-performance solvents are a must. LiChrosolv® solvents are designed to optimally support analytical HPLC, fast chromatography, a...
Keywords: Chromatography, Evaporation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Phase transitions, Separation, Solvents

Thin Layer Chromatography Identification Test for Folic Acid following European Pharmacopeia Monograph on Silica Gel G F 254 Plates

Folic acid, known as folate in its natural form, is a water soluble compound known as vitamin B9. Folic acid is vital to the body in small amounts, and can found in whole-grain breads, cereals, liver...
Keywords: Solvents, Thin layer chromatography, Vitamins

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