1.03132 Supelco


for liquid chromatography LiChrosolv®

Synonym: 1,4-Dioxane, Glycolethylether, 1,4-Diethylene dioxide, 1,4-Dioxacyclohexane

  • CAS Number 123-91-1

  • Empirical Formula (Hill Notation) C4H8O2

  • Molecular Weight 88.11

  •  MDL number MFCD00006571

  •  EC Index Number 204-661-8



Related Categories HPLC Grade Solvents, HPLC Solvents, Solvent by Application, Solvents
Quality Level   100
vapor pressure   41 hPa ( 20 °C)
assay   ≥99.8% (GC)
form   liquid
autoignition temp.   300 °C
potency   5200 mg/kg LD50, oral (Rat)
  7600 mg/kg LD50, skin (Rabbit)
expl. lim.   1.7-25.2 % (v/v)
application(s)   LC/MS: suitable
pH   6-8 (20 °C, 500 g/L in H2O)
bp   101.5 °C/1013 hPa
mp   12 °C
transition temp   flash point 11 °C
density   1.03 g/cm3 at 20 °C
InChI   1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
storage conditions   Store at +5°C to +30°C.


General description

With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.

Analysis Note

Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.02 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 245 nm): ≥ 50 %
Transmission (at 270 nm): ≥ 80 %
Transmission (from 300 nm): ≥ 98 %
Filtered by 0.2 µm filter

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Protocols & Articles


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