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1.04820 SAFC

Potassium acetate

extra pure Ph Eur,BP,JPE,E 261

Synonym: Potassium acetate

  • CAS Number 127-08-2

  • Empirical Formula (Hill Notation) C2H3KO2

  • Molecular Weight 98.14

  •  MDL number MFCD00012458

  •  E Number E261

  •  EC Index Number 204-822-2

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Properties

Related Categories APIs (Active Pharmaceutical Ingredients) and Excipients, Biopharmaceutical Process Development and Manufacturing, Excipients, Liquid Dosage Forms, Mineral Salts,
Agency/Method   BP
  JPE
  Ph Eur
Quality Level   400
potency   3250 mg/kg LD50, oral (Rat)
pH   7.5-8.5 (20 °C, 50 g/L in H2O)
mp   292 °C
density   1.57 g/cm3 at 25 °C
bulk density   500 kg/m3
InChI   1S/C2H4O2.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1
InChI key   SCVFZCLFOSHCOH-UHFFFAOYSA-M
storage conditions   Store at +5°C to +30°C.

Description

Analysis Note

Assay (perchloric acid titration, calculated on dried substance): 99.0 - 100.5 %
Identity: passes test
Appearance of solution: passes test
pH-value (5 %; water): 7.5 - 8.5
Chloride (Cl): ≤ 0.01 %
Sulfate (SO₄): ≤ 0.005 %
Heavy metals (as Pb): ≤ 0.0004 %
Al (Aluminium): ≤ 0.0001 %
As (Arsenic): ≤ 0.0002 %
Fe (Iron): ≤ 0.001 %
Hg (Mercury): ≤ 0.0001 %
Na (Sodium): ≤ 0.5 %
Pb (Lead): ≤ 0.0002 %
free acetic acid: ≤ 0.4 %
Other residual solvents (ICH Q3C): excluded by manufacturing process
Substances reducing potassium permanganate (as HCOOH): passes test
Loss on Drying (105 °C): ≤ 3.0 %
formic acid, formate and other oxidizable impurities: ≤ 0.1 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph.Eur., BP, JPE, E261
Conforms to the purity criteria on food additives according to the current European Commission Regulation.

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