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1.37123 SAFC

Benzalkonium chloride



Synonym: Alkylbenzyldimethylammonium chloride, Alkyldimethylbenzylammonium chloride

  • CAS Number 63449-41-2

  • Linear Formula C6H5CH2N(CH3)2RCl (R=C8H17 to C18H37)

  •  Beilstein/REAXYS Number 4062599

  •  UBA Number 12352200

  •  MDL number MFCD00145757

  •  PubChem Substance ID 24847423



Agency/Method   NF
  Ph. Eur.
Quality Level   500
product line   EMPROVE® Expert
packaging   pkg of 1 kg
SMILES string   [Cl-].CCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1
InChI   1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1


General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.


Benzalkonium chloride is typically used as preservative in liquid formulations, e.g. for topic, ophthalmic, nasal and parenteral applications. It is effective against a wide range of bacteria, yeast and fungi.
Due to a defined C12:C14 ratio with high batch-to-batch consistency, Benzalkonium chloride Emprove® EXPERT provides higher solubility and antimicrobial activity. It can be used in combination with thimerosal, disodium edetate and benzyl alcohol to further increase antimicrobial activity.
This product is also available as 50% aqueous solution (Art.No. 137124).
The specification of the product is part of the Emprove® Material Qualification Dossier and can be found under "General Properties".


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Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

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