• USA Home
  • 208670 - Calmodulin, His•Tag Human, Recombinant

EMAIL THIS PAGE TO A FRIEND
208670 Sigma-Aldrich

Calmodulin, His•Tag Human, Recombinant

Calmodulin, His•Tag® Human, Recombinant, is a full-length, recombinant human calmodulin fused to a His•Tag® sequence at the N-terminus. Contains four functional Ca2+-binding sites.

Synonym: Calmodulin, Human, Recombinant, Calmodulin, Human, Recombinant

Purchase

Properties

Related Categories Apoptosis and Cell Cycle, Auxiliary Proteins, Biochemicals and Reagents, Cell Biology, Cell Cycle Proteins, Antibodies and Reagents,
packaging   50 μg in Plastic ampoule (208670-50UG)
brand family   Calbiochem
form   Liquid
purity   >90% by SDS-PAGE
storage conditions   Avoid freeze/thaw
  Ok to freeze
shipped in   wet ice
storage conditions   = -70C

Description

General description

Full-length, recombinant human calmodulin fused to a HisTag sequence at the N-terminus. Contains four functional Ca2+-binding sites (aa 20-31; aa 56-67; aa 93-104; aa 129-140) with EF-hands (aa 7-42; aa 43-78; aa 80-115; aa 116-148); and a ubiquitination site at Lys21. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Through its interaction with Ca2+, calmodulin mediates the control of a large number of enzymes, including protein kinases and phosphatases. It is expected to be phosphorylated at Thr44 by CaMK4. In addition, it serves as a substrate for various protein tyrosine kinases.

Other Notes

Chou, J.J., et al. 2001.Nat. Struct. Biol.8, 990.
Lennon, G., et al. 1996.Genomics33, 151.

Packaging

Please refer to vial label for lot-specific concentration.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Warning

Standard Handling (A)

Physical form

In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?