• USA Home
  • 219011 - InSolution Caspase Inhibitor VI - Calbiochem

EMAIL THIS PAGE TO A FRIEND
219011 Sigma-Aldrich

InSolution Caspase Inhibitor VI - Calbiochem

The InSolution™ Caspase Inhibitor VI, also referenced under CAS 161401-82-7, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.

  • Empirical Formula (Hill Notation) C21H28FN3O7

  • Molecular Weight 453.46

Purchase

Properties

Related Categories A to C, Bioactive Small Molecules, Biochemicals and Reagents, Caspase, Cell Biology,
packaging   1 mg in Glass bottle (219011-1MG)
form   liquid
shipped in   wet ice
storage condition   OK to freeze
  desiccated
  protect from light
brand family   Calbiochem
purity   ≥95% by TLC
storage conditions   -20C

Description

Biochem/physiol Actions

Cell permeable: yes

Primary Target
general caspase inhibitor

Product does not compete with ATP.

Reversible: no

General description

A cell-permeable, irreversible, and general caspase inhibitor. Also reported to inhibit Peptide: N-glycanase (PNGase) in vitro and in vivo. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies.

Other Notes

Misaghi, S., et al. 2004. Chem. Biol.11, 1677.

Packaging

1 mg in Glass bottle

Packaged under inert gas

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 3 months at -20°C.

Warning

B

Physical form

A 10 mM (1 mg/221 µl) solution of Caspase Inhibitor VI (Cat. No. 219007) in DMSO.

Sequence

Z-Val-Ala-Asp-CH₂F*

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?