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219421 Sigma-Aldrich

Cathepsin L Inhibitor I - CAS 108005-94-3 - Calbiochem

The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym: Cathepsin L Inhibitor I - CAS 108005-94-3 - Calbiochem, Z-FF-FMK

  • CAS Number 108005-94-3

  • Empirical Formula (Hill Notation) C27H27FN2O4

  • Molecular Weight 462.51

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Properties

Quality Level   100
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   -20C
color   white
solubility   DMSO: 20 mM
shipped in   ambient

Description

General description

A potent, cell-permeable and irreversible inhibitor of cathepsin L.

A potent, cell-permeable, and irreversible inhibitor of Cathepsin L (Cat. No. 219402).

Packaging

1 mg in Plastic ampoule

Biochem/physiol Actions

Cell permeable: yes

Primary Target
cathepsin L

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Phe-Phe-CH₂F

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Analysis Note

single spot by TLC

Other Notes

Ravanko, K., et al. 2004. Cancer Res.64, 8831.
Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.
Shaw, E., et al. 1993. FEBS Lett.334, 340.

Safety & Documentation

Safety Information

Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
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