• USA Home
  • 230950 - Ciglitazone - CAS 74772-77-3 - Calbiochem

EMAIL THIS PAGE TO A FRIEND
230950 Sigma-Aldrich

Ciglitazone - CAS 74772-77-3 - Calbiochem

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC₅₀ = 3 µM).

Synonym: (±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I, (±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I

  • CAS Number 74772-77-3

  • Empirical Formula (Hill Notation) C18H23NO3S

  • Molecular Weight 333.45

Purchase

Properties

Related Categories Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, PPAR and RXR Regulators More...
brand family   Calbiochem
feature productdata solubility   DMSO (≥ 25 mg/ml) or Ethanol (≥25 mg/ml)
form   Tan solid
packaging   5 mg in Plastic ampoule (230950-5MG)
primary target IC50   EC50 = 3 µM as PPARγ agonist
purity   ≥98% by HPLC
shipped in   ambient
storage conditions   +2C to +8C
  Ok to freeze

Description

Biochem/physiol Actions

Cell permeable: no

Primary Target
Selective PPARγ agonist

Product does not compete with ATP.

Reversible: no

General description

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).

Other Notes

Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.

Reconstitution

Stock solutions are stable for up to 3 months at -20°C.

Warning

Harmful (C)

Safety & Documentation

Safety Information

RTECS 
XJ5813700
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?