• USA Home
  • 231085 - Cilostamide - CAS 68550-75-4 - Calbiochem

EMAIL THIS PAGE TO A FRIEND
231085 Sigma-Aldrich

Cilostamide - CAS 68550-75-4 - Calbiochem

A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC₅₀ = 70 nM).

Synonym: Cilostamide - CAS 68550-75-4 - Calbiochem, N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide, OPC 3689

  • CAS Number 68550-75-4

  • Empirical Formula (Hill Notation) C20H26N2O3

  • Molecular Weight 342.43

Purchase

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, Phosphodiesterase Inhibitors More...
Quality Level   100
assay   ≥98% (TLC)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
storage conditions   +2C to +8C
color   white
solubility   DMSO: 5 mg/mL
shipped in   ambient

Description

General description

A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 70 nM).

Packaging

10 mg in Plastic ampoule

Biochem/physiol Actions

Cell permeable: yes

Primary Target
PDE 3

Product does not compete with ATP.

Reversible: no

Target IC50: 70 nM against PDE III

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Other Notes

Verghese, M.W., et al. 1995. J. Pharmacol. Exp. Ther. 272, 1313.
Christensen, S.B., and Trophy, T.J. 1994. Ann. Rep. Med. Chem. 29, 185.
Tang, K.M., et al. 1994. Eur. J. Pharmacol. 268, 105.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?