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239900 Sigma-Aldrich

Cypermethrin - CAS 52315-07-8 - Calbiochem

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Synonym: Cypermethrin - CAS 52315-07-8 - Calbiochem

  • CAS Number 52315-07-8

  • Empirical Formula (Hill Notation) C22H19Cl2NO3

  • Molecular Weight 416.30

  •  MDL number MFCD00055328

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Properties

Quality Level   100
assay   ≥95% (HPLC)
form   oil
mfr. no.   Calbiochem®
storage condition   OK to freeze
storage conditions   +2C to +8C
solubility   DMSO: 15 mg/mL
  ethanol: 5 mg/mL
shipped in   ambient
InChI   1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
InChI key   KAATUXNTWXVJKI-UHFFFAOYSA-N

Description

General description

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.

Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 40 pM). May also have varied effects on ion channels.

Packaging

10 mg in Alu drum

Biochem/physiol Actions

Primary Target
calcineurin

Product does not compete with ATP.

Target IC50: 40 pM against calcineurin (protein phosphatase 2B

Warning

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.

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